Professor Mary Morrell, is the Director of Phase One. She is a Professor of Sleep and Respiratory Physiology, at Imperial College School of Medicine in the National Heart and Lung Institute at the Royal Brompton Hospital. Mary’s research focuses on the causes and consequences of breathing disorders during sleep; particularly the impact of hypoxia on the brain. The aim of her research group is to translate physiological research into improvements in patient care. Recently, she developed a UK respiratory-sleep network facilitating multi-centre trials. The network has previously completed a trial to determine the impact of treating OSA in older people, and more recently the treatment of mild OSA. Mary has served on the American Thoracic Society Board of Directors, the Physiological Society Executive Board and she is a Past-President of the British Sleep Society.