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Antimicrobial resistance - theory and methods に戻る

Antimicrobial resistance - theory and methods, デンマーク工科大学(Technical University of Denmark(DTU))



The course will cover the topics related to antimicrobial resistance with basic definitions and overview on antimicrobials their use and the emergence and spread of resistance. The course will guide you through the concepts and the importance of resistance spread and dissemination and how that happens. It will show you how bacteria become resistant and which mechanisms they might use for this. And as part of the course you will also receive some training in methods for antimicrobial susceptibility testing (AST) and detection of specific resistance in the microbiological laboratories with the basic methods available and with focus on the obtention of good quality results which can be interpreted and used for different purposes. Additionally, it will show you how to use genomic analysis tools to analyze whole genome sequencing data to detect resistance genes (and or other genes of interest) in a simple and easy way using online tools freely available. In the new new version an additional module including detection of specific resistance mechanisms was added. After this course you should be able to: 1. Describe the most important families of antimicrobials and mode of action 2. Understand the basic concepts of antimicrobial resistance from several perspectives (clinical, research and microbiological) 3. Enumerate and describe how bacteria can become resistant and the mechanisms that may be involved in that process 4. Describe how antimicrobial resistance emerges and spreads around the world including concepts of antimicrobial resistance transfer, selection and dissemination 5. Enumerate the methods used for antimicrobial susceptibility testing (AST) 6. Compare dilution and diffusion methods and know the basic techniques of agar disk diffusion, broth dilution and agar dilution methods 7. Have detailed theoretical knowledge on how to perform the main methods in a laboratory 8. Know the basic concepts about analysis and interpretation of results of AST, including different breakpoints, cut-off setting and their applications. 9. Understand the importance and related concepts related to quality management and quality assurance method standardization, applied to AST 10. Relate the information obtained in this course with real cases of resistant bacteria spreading in patients, the community, animals or the environment 11. Relate the phenotypical results with results from genotyping using molecular techniques for detection of resistance mechanisms 12. Understand the concept and be able to apply genomic analysis tools used to detect resistance genes and other relevant genes from Whole Genome Sequencing (WGS) data (with demonstration of selected online tools) Disclaimer: Please note that the guidelines and methods referred or links included in these materials are updated when the videos lectures are produced and before the course is released, however these might become outdated with time....


by DJ

Nov 15, 2016

It was really a good lectures and please I want to know about my certificate in have already purchased this course and submitted all\n\nThe documents let me know when will I get my certificate .

by AA

Sep 24, 2017

This i very good course. i recommended to all microbiology and molecular biology students. All three teachers are very good. specially last week lecture about molecular detection of MRSA. CRE.



by Maria Celeste Pellegrini

May 21, 2019

exelente! gracias!

by Angela Paredes López

May 14, 2019

Please more courses about resistance. Thank you.

by Jose William Martínez

May 05, 2019

Excelent lectures

by Paulina Carreño Pérez

Apr 08, 2019

Un Curso Excelente para introducirse al tema y aclarar las dudas que salen durante la práctica diaria.


Mar 26, 2019

I miss more reference articles during the course.

by Aman Ullah

Mar 07, 2019

I found this course very informative and up to the marks and I really enjoyed the course

by vijay shankar

Feb 21, 2019

it is really a good course for a microbiology student, i learned lots of things.

please add more practical evidences and discussions, if possible.

by Dulce Argelia Camacho Bravo

Feb 08, 2019


by John Gatimu

Feb 02, 2019

Great course and so relevant esp in Africa. AMR is a big growing problem

by Rafshan Jahan

Feb 01, 2019

One of the fine course for developing basics as well as advanced level of antimicrobial resistance.Very co-operative,easy instructions to understand.