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英語

字幕:英語

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BiologyMicrobiologyPublic HealthVaccine Development

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自分のスケジュールですぐに学習を始めてください。

柔軟性のある期限

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約15時間で修了

推奨:20 hours of videos and quizzes...

英語

字幕:英語

シラバス - 本コースの学習内容

1
1時間で修了

Course Introduction

Welcome to Epidemics: the Dynamics of Infectious Diseases. This course will teach you about the variety of parasitic organisms that infect humans, animals, and plants, how these parasites spread through populations, and the various methods that we employ to control them....
3 readings
3件の学習用教材
Course Overview10 分
Course Syllabus10 分
Glossary of Terms10 分
1時間で修了

Pathogens

In the first module, you will learn about the organisms that can infect us and make us sick: pathogens. We will first take a look at the various types of pathogens that exist, and then learn about what it means to be infectious, and what it means to cause disease. After that, we will cover the various methods by which pathogens can transmit from one person to the next, thereby causing an epidemic. You will learn about the most important number in all of epidemiology, R0, and why this number is so important. Finally, we will learn that microorganisms are not always harmful, but can be beneficial to us as well....
7件のビデオ (合計40分), 1 reading, 1 quiz
7件のビデオ
Micro and Macro Parasites5 分
Infection and Disease6 分
Transmission Types4 分
Reproductive Number4 分
Epidemic Curve6 分
Micro-organisms6 分
1件の学習用教材
Module Overview10 分
1の練習問題
Summative: Pathogens20 分
2
1時間で修了

Hosts

The second module of the course covers host factors that determine the outcome of infection. We will first focus on host immunity and present both the general immune capabilities—the innate immune response—that are encoded in our genes and that provide the initial response to infection and the adaptive immune response, which arises from highly specialized cells that protect against a specific pathogen. You will then learn about the ways that pathogens circumvent these two types of immunity and consider other factors that can contribute to an individual becoming infected or diseased—including genetic factors, other microbes, and how social and emotional factors influence immunity. We will then consider how infection with a microorganism causes disease and how public health officials determine whether a disease outbreak is caused by an infectious organism....
7件のビデオ (合計41分), 1 reading, 1 quiz
7件のビデオ
Types of Immunity: Adaptive Immune System5 分
Immune Evasion6 分
Other Determinants of Susceptibility6 分
Social Influences on Immunity4 分
Pathogens and Disease6 分
Detecting an Infectious Disease Outbreak6 分
1件の学習用教材
Module Overview: Hosts10 分
1の練習問題
Summative: Hosts20 分
3
1時間で修了

Basics of Ecology

The third module of the course covers ecological factors that influence the dynamic patterns of infectious disease. We will discuss the conditions under which a pathogen can drive its host to extinction. We will look at how the demography of the host may allow the pathogen to persist in some populations but not others. We will talk about how host and pathogen characteristics interact to shape different temporal patterns of disease incidence at the population level and discuss the ecological consequences of infecting more than one host species....
9件のビデオ (合計55分), 1 reading, 1 quiz
9件のビデオ
Force of Infection5 分
Cycles4 分
Seasonality3 分
Flu 19185 分
Host Diversity, Host Range3 分
Critical Community Size8 分
Pathogen-Microbiome Interactions8 分
The 2014 Ebola Outbreak9 分
1件の学習用教材
Module Overview: Basics of Ecology10 分
1の練習問題
Summative: Basics of Ecology20 分
4
1時間で修了

Epidemiology

Where humans live and how they are connected to each other, have strong effects on how infectious diseases can spread. In this module, you will learn about some of the related key concepts of epidemiology. After looking at some fascinating history, we’ll learn about social networks as the ultimate “road map” on which diseases can travel and we’ll talk about how the structure of the network can influence disease dynamics. After that, we’ll cover three topics that all affect infectious disease epidemiology in dramatic ways: human transport systems, population density and so-called superspreaders - individuals who can spread a disease to dozens or even hundreds of other individuals. We’ll close by identifying what information is required for disease surveillance....
8件のビデオ (合計52分), 1 reading, 1 quiz
8件のビデオ
Social Networks5 分
Structure of Networks5 分
Superspreaders6 分
Spatial Hetergeneity5 分
Movement and Modern Transportation5 分
Surveillance and Disclosure5 分
Co-Infection Consequences10 分
1件の学習用教材
Module Overview: Epidemiology10 分
1の練習問題
Summative: Epidemiology20 分
5
1時間で修了

Vaccination

In module 5 of the course, you will learn about vaccination, one of the most common approaches to the prevention of epidemics. We'll first put vaccination in the context of the many types of public health interventions that that can be used to prevent or treat disease. After that you will learn about the development of the first vaccine, how vaccines work to prevent infection, and the impact that vaccination has had on the prevention of disease worldwide. After that, you will learn about how vaccination can provide protection to everyone, even the unvaccinated, in the population through "herd immunity" and how we can use the structure of social networks within populations to more efficiently achieve this herd protection. Finally we'll learn about how individuals choices about whether or not to get vaccinated can lead to impacts across the whole of the population....
7件のビデオ (合計40分), 1 reading, 1 quiz
7件のビデオ
Discovery of the First Vaccine3 分
Global Impact of Vaccination6 分
How Vaccination Works7 分
Herd Immunity5 分
Social Networks and Targeted Vaccination6 分
Vaccination Refusal5 分
1件の学習用教材
Module Overview: Vaccination10 分
1の練習問題
Summative: Vaccination20 分
6
2時間で修了

Control Mechanisms

In module 6 of the course, you will learn about mechanisms involved in controlling epidemics. In these lectures, we will discuss what control mechanisms are trying to do, such as breaking the chain of transmission, and many ways by which animals and humans attempt to achieve control. These means include pharmaceutical and non-pharmaceutical interventions, appearing at individual or population levels. We will describe examples of great successes in eradication, and the reasons why control efforts fail....
10件のビデオ (合計63分), 1 reading, 1 quiz
10件のビデオ
Social Challenges to Eradication4 分
Non-pharmaceutical Interventions: Animals5 分
Non-pharmaceutical Interventions: Humans 14 分
Non-pharmaceutical Interventions: Humans 27 分
Behavioral Avoidance6 分
Controlling the Vector8 分
Consequences of Control7 分
Vaccination Ethics7 分
New Approaches to an Old Infection5 分
1件の学習用教材
Module Objectives: Control Mechanisms10 分
1の練習問題
Summative: Control Mechanisms20 分
7
1時間で修了

Emergence

In module 7 of the course, we’ll look at so-called emerging infectious diseases. These are diseases that are causing new problems. They include infectious agents that are new to humanity, but also infectious agents that were once controlled and are now returning, particularly those that are evolving around formerly very effective public health tools like drugs and vaccines. This means much of the week involves a discussion of evolution. We will look at these emerging diseases and ask, where do they come from and what can be done about them? You will learn about new ideas for managing evolution, and some of the societal challenges involved. We will also look at the related question of how some diseases evolve to be nicer or nastier to their hosts....
7件のビデオ (合計49分), 1 reading, 1 quiz
7件のビデオ
Re-emergence5 分
Evolution General5 分
Antibiotic and Drug Resistance5 分
Management of Resistance8 分
Behavioral And Economic Impact5 分
Evolution of Virulence8 分
1件の学習用教材
Module Overview: Emergence10 分
1の練習問題
Summative: Emergence20 分
8
1時間で修了

Global Health

In this final module we explore the global context of epidemics. The world is rapidly changing with the global population increasing and the speed of travel and extent of globalization piling on the pressure of infectious diseases. In this week we set out first to explore a textbook example of disease shaped by the conditions presented by modern living: the disease SARS. We will see how high density living in cities coupled with links to wildlife diseases through markets can create a pandemic. We then explore traditional methods of disease surveillance and then more recent ones afforded to us by the web and networks made possible through google, twitter and other social media. Important to this global view is human behavior, our evolving culture and health. We will also consider emerging disease and the global pattern of diseases across our recent history and how from our earliest beginnings of global travellers we have affected the spread of diseases. Finally, we discuss disease of our food plants and how models of disease spread are developed to promote better global health. As a postscript to the course we ask the questions, so beloved of modern media, could we become zombies?...
9件のビデオ (合計55分), 1 reading, 1 quiz
9件のビデオ
Disease Surveillance - Classical7 分
Disease Surveillance - Digital5 分
Culture and Health5 分
Emerging Disease Issues7 分
Crop Diseases and Food Security5 分
Global Pattern of Parasite Biodiversity4 分
Models of Infectious Diseases7 分
Zombies6 分
1件の学習用教材
Module Overview: Global Health10 分
1の練習問題
Summative: Global Health20 分
4時間で修了

Ask Us Anything Videos

The videos accessible in this module are responses to questions that have been posed in previous sessions of this course. We invite you to look around here as an additional resource to answer questions you might have yourself or explore topics that pique your interest. ...
36件のビデオ (合計261分)
36件のビデオ
What Does It Mean to Be Infectious?4 分
What is the Impact of Prior Infections on Susceptibility to New Pathogens?5 分
What Ended the Plague? What Can We Learn About Pandemics?5 分
Can Behavior Contribute to Susceptibility?6 分
Marilyn Roosinck and What’s Different about Plant Epidemiology?8 分
Can Plants be Vectors of Disease?4 分
What are Other Determinants of Susceptibility?5 分
Can Pathogens Change Host Function?5 分
Immune System Conflict6 分
Eric Harvill and What is the Whole Micro-Biome, Pro-Biotic, Good Bacteria Thing?6 分
Why Can't Our Antibodies Mutate Like Antigens?4 分
How Does Microbiome Exchange Therapy Work?8 分
What are the Best Strategies to Combat Multi-Species Infections?7 分
How Relevant is the Concept of Critical Community Size?7 分
Isabella Catadori and the Translation of Her Lab Work into the Field5 分
Examples of Co-Infections and How They Change Epidemiology of Human Infections6 分
Super-Shedders v. Super Spreaders and the Pareto Principle6 分
The Role of Social Media in Epidemiology and how Information is Disseminated8 分
Dr. Vivek Kapur and What Do We Need to Know about Development and Implementation of New Vaccines?9 分
Why Don't We Have Vaccines for Everything?8 分
Why Don't We Use Targeted Vaccinations?7 分
What Are the Benefits of So-Called Gain-of-Function Experiments?11 分
Dr. Moriah Szpara and How/Why do viruses like Varicella and Herpes Re-activate Themselves?7 分
What are the Challenges to the Eradication of Pathogens and Setting Eradication as a Goal?6 分
How Does Stress Affect Susceptibility and the Expression of Disease?6 分
Has there been a Collective Change in Human Behavior in Response to Sexually Transmitted Diseases?9 分
What can we do to minimize selection for resistance in vectors?8 分
Genetic engineering of vectors? pt.17 分
Genetic engineering of vectors? pt.27 分
What is the role of climate change in disease emergence?8 分
What can we learn from antibiotic and vaccine use in agriculture? 7 分
Dr. Craig Cameron and What do We Mean by 'Antivirals?'8 分
What is it About Polio?9 分
What About the One Health Concept?7 分
What is the Next Big Thing?8 分
4.7
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人気のレビュー

by DBApr 23rd 2016

Can't fault this course at all and nor would I want to. Very interesting, brilliantly presented and the range of experts really enhanced it. It was engaging and made me keen to find out more.

by DJMay 13th 2017

It is a wonderful course , I have gain and updated my Knowledge in the area of Epidemics and Infectious Disease, Thanks to the Course organizers and most effective presentations . Dr Shivaji

講師

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Dr. Ottar N. Bjornstad

Professor of Entomology and Biology
Department of Biology
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Dr. Rachel A. Smith

Associate Professor
Department of Communication Arts & Sciences and Human Development & Family Studies
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Dr. Mary L. Poss

Professor of Biology
Department of Biology
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Dr. David P. Hughes

Assistant Professor of Entomology and Biology
Department of Biology
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Dr. Peter Hudson

Willaman Professor of Biology
Department of Biology
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Dr. Matthew Ferrari

Assistant Professor of Biology
Department of Biology
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Dr. Andrew Read

Alumni Professor in the Biological Sciences, and Professor of Entomology
Center for Infectious Disease Dynamics
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Dr. Marcel Salathé

Assistant Professor of Biology
Department of Biology

ペンシルベニア州立大学(The Pennsylvania State University)について

Founded in 1855 as Pennsylvania's only land-grant university, The Pennsylvania State University combines academic rigor with a vibrant campus life. A nationally recognized Research-I institution, Penn State teaches students to be leaders with a global perspective. Supporting not only the citizens of our Commonwealth, Penn State engages in collaborative activities with industrial, educational, and agricultural partners in the United States and abroad to generate, disseminate, integrate, and apply knowledge that is valuable to society....

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