This course covers approaches for modelling treatment of infectious disease, as well as for modelling vaccination. Building on the SIR model, you will learn how to incorporate additional compartments to represent the effects of interventions, such the effect of vaccination in reducing susceptibility. You will learn about ‘leaky’ vaccines and how to model them, as well as different types of vaccine and treatment effects. It is important to consider basic relationships between models and data, so, using the basic SIR model you have developed in course 1, you will calibrate this model to epidemic data. Performing such a calibration by hand will help you gain an understanding of how model parameters can be adjusted in order to capture real-world data. Lastly in this course, you will learn about two simple approaches to computer-based model calibration - the least-squares approach and the maximum-likelihood approach; you will perform model calibrations under each of these approaches in R.
Infectious Disease Modelling の専門講座インペリアル・カレッジ・ロンドン（Imperial College London）このコースについて
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インペリアル・カレッジ・ロンドン（Imperial College London）
Imperial College London is a world top ten university with an international reputation for excellence in science, engineering, medicine and business. located in the heart of London. Imperial is a multidisciplinary space for education, research, translation and commercialisation, harnessing science and innovation to tackle global challenges.
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シラバス - 本コースの学習内容
Modelling Interventions
Once you have captured the basic dynamics of transmission using simple mathematical models, it is possible to use these models to simulate the impact of different interventions. You will study approaches for modelling treatment of infectious disease, as well as for modelling vaccination. Building on the SIR model, you will learn how to incorporate additional compartments to represent the effects of interventions (for example, the effect of vaccination in reducing susceptibility). You will learn about ‘leaky’ vaccines and how to model them, as well as different types of vaccine and treatment effects.
Confronting Models with Data - Part A
All models answering public health questions first need to be matched, or ‘calibrated’, against real-world data to ensure that model-simulated dynamics are consistent with what is observed. In this module, you will consider basic relationships between models and data. Using the basic SIR model that you've developed so far, you will calibrate this model to epidemic data. Through performing this calibration by hand, you'll gain an understanding of how model parameters can be adjusted so as to order to capture real-world data.
Confronting Models with Data - Part B
In practice model calibration for compartmental models is rarely done by hand. Rather, we construct a function that summarises the goodness-of-fit between the model and the data and then use available computer algorithms to maximise this goodness-of-fit. In these next two modules, you will learn about two simple approaches to computer-based model calibration: the least-squares approach and the maximum-likelihood approach. You will perform model calibrations under each of these approaches in R.
Confronting models with data – Part C
Please note - learning outcomes are the same across both this and the last module. In practice, model calibration for compartmental models is rarely done by hand. Rather, we construct a function that summarises the goodness-of-fit between the model and the data and then use available computer algorithms to maximise this goodness-of-fit. In these two modules, you'll learn about two simple approaches to computer-based model calibration: the least-squares approach, and the maximum-likelihood approach. You will perform model calibrations under each of these approaches in R.
レビュー
INTERVENTIONS AND CALIBRATION からの人気レビュー
Such a great learning experience. The course provided me with a comprehensive overview of the topics under concern. My gratitude to the instructors for creating such a valuable course.
A great learning experience, have to struggle a lot for the quiz, But in the end it helps to get better understanding of the concept and practice.
Excellent course videos, content, assignment quiz. Received very good support from instructor and other members/ learners on discussion forum.
Excellent course led from first course right into this course perfectly. Level is perfect assignments perfect. Already told 5 people about it.
Infectious Disease Modelling専門講座について
Mathematical modelling is increasingly being used to support public health decision-making in the control of infectious diseases. This specialisation aims to introduce some fundamental concepts of mathematical modelling with all modelling conducted in the programming language R - a widely used application today.
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この専門講座をサブスクライブすると何を行うことができるようになりますか？
コースに登録する際、専門講座のすべてのコースにアクセスできます。コースの完了時には修了証を取得できます。電子修了証が成果のページに追加され、そこから修了証を印刷したり、LinkedInのプロフィールに追加したりできます。コースの内容の閲覧のみを希望する場合は、無料でコースを聴講できます。
Is financial aid available?
サブスクライブすると、7日間の無料トライアルを体験できます。この期間中は解約金なしでキャンセルできます。それ以降、払い戻しはありませんが、サブスクリプションをいつでもキャンセルできます。返金ポリシーをすべて表示します。
Will I earn university credit for completing the Course?
はい。受講料の支払いが難しい受講生に、Coursera（コーセラ）は学資援助を提供しています。左側の［登録］ボタンの下にある［学資援助］のリンクをクリックして申請してください。申請書の入力を促すメッセージが表示され、承認されると通知が届きます。キャップストーンプロジェクトを含む専門講座の各コースでこのステップを完了する必要があります。詳細。
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