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Whole genome sequencing of bacterial genomes - tools and applications に戻る

デンマーク工科大学(Technical University of Denmark(DTU)) による Whole genome sequencing of bacterial genomes - tools and applications の受講者のレビューおよびフィードバック

4.6
877件の評価
237件のレビュー

コースについて

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

人気のレビュー

AP
2020年7月19日

Thank you very much for this course through which i learnt basic handling of bioinformatics tools and concepts of WGS. This will help me a lot while pursuing my PhD research work in my field.

MB
2019年6月9日

Excellent course with a wealth of information about tools and applications of whole genome sequencing. Presented in a very lucid and interesting manner, very crispy and simplified course.

フィルター:

Whole genome sequencing of bacterial genomes - tools and applications: 226 - 236 / 236 レビュー

by Arina D

2020年7月1日

This is a set of manuals. No theory - just a description of several tools with some very basic explanation of the principles underlying these tools.

Before applying for this course, I can suggest visiting the site with all the tools described in these courses and reviewing it - it may be easier for someone (and definitely faster) to read the instructions on the site https://cge.cbs. dtu.dk/services/

However, the tools themselves are quite useful.

by Lynn M

2020年9月18日

Was slightly disappointed about how the class is very on the surface. It covers some cool tools but does not go into the details of genome sequencing, which I was expecting to see more of. Some lectures are highly repetitive as well.

by Lydia S

2020年4月26日

Got only rudimental knowledge of WGS but more detailed information how to use their pipelines- seems like a more commerical course than learning element.

I'd like the other course about antimicrobial resistance much better.

by Frédéric B G

2019年11月11日

This course has been mainly constructed to explain how the full set of bioinformatic tools developed by the CGE of DTU can be used. Personally, I would have preferred a course with more theoretical basis.

by James P

2020年8月12日

I thought this would be informative but the entire course is basically an infomercial for using their web based tools. Which to some, could be helpful but any serious bioinformatician should avoid.

by Luisa F D B

2020年6月22日

I liked some of the sections but the course is really focused on the platform developed by its university, so despite it is useful it does not give examples of another tool like BLAST

by Franziska N

2020年10月1日

Good lectures, but unfortunately there is little general background transferred through this course. The lectures and the quiz seem mainly to be advertisement for their tools.

by Harvey T

2019年10月29日

the presentation skills and the language were not so high. some files that need analysis are not working. But it is useful course by the end.Thx alot

by Jing C

2017年11月14日

Wish it was more concise.

by Luka G

2020年6月5日

The course itself is great, unfortunately the person who designed it and is the main speaker has incomprehensible English, to a point that one needs triple the exertion to understand her. The transcript of the speech seems to be automatically generated, so one can not even read the lecture to understand it.

by Catherine M

2020年10月23日

Can not even pass the first quiz, even with correct answers. The two videos based off the questions don't answer some of the questions if at all, and a google search or more in depth search revealed the correct answers, however the quiz continued to be incorrect no matter what correct answers you gave it.