SARS-CoV-2, the virus that causes COVID-19, poses a high risk for assisted living communities due to residents’ age, health status, and communal living environment. The COVID-19 response has largely focused on nursing homes, leaving assisted living communities in the United States with fragmented guidance on how to respond to COVID-19 challenges. This course provides comprehensive instruction and resources for administrators and direct-care staff of assisted living communities. Learners will hear from experts about best practices to prevent COVID-19 outbreaks and promote well-being. Topics discussed include development of emergency preparedness plans, infection and outbreak prevention, staffing considerations, testing, and contact tracing. The course also covers strategies for communicating with stakeholders, promoting resident and staff well-being, and leveraging health departments and other agency resources, including a collection of resources for COVID-19 vaccination guidance. Learners are encouraged to concurrently develop and enhance their own community’s policies, procedures, and practices. This course was developed in partnership with the Baltimore City Health Department.