この専門講座について

100%オンラインコース

自分のスケジュールですぐに学習を始めてください。

フレキシブルなスケジュール

柔軟性のある期限の設定および維持

中級レベル

約6か月で修了

推奨5時間/週

英語

字幕:英語, 中国語(簡体)

習得するスキル

BiologyMolecular BiologyDynamical SystemsMatlab

100%オンラインコース

自分のスケジュールですぐに学習を始めてください。

フレキシブルなスケジュール

柔軟性のある期限の設定および維持

中級レベル

約6か月で修了

推奨5時間/週

英語

字幕:英語, 中国語(簡体)

専門講座のしくみ

コースを受講しましょう。

Coursera(コーセラ)の専門講座は、一連のコース群であり、技術を身に付ける手助けとなります。開始するには、専門講座に直接登録するか、コースを確認して受講したいコースを選択してください。専門講座の一部であるコースにサブスクライブすると、自動的にすべての専門講座にサブスクライブされます。1つのコースを修了するだけでも結構です。いつでも、学習を一時停止したり、サブスクリプションを終了することができます。コースの登録状況や進捗を追跡するには、受講生のダッシュボードにアクセスしてください。

実践型プロジェクト

すべての専門講座には、実践型プロジェクトが含まれています。専門講座を完了して修了証を獲得するには、成功裏にプロジェクトを終了させる必要があります。専門講座に実践型プロジェクトに関する別のコースが含まれている場合、専門講座を開始するには、それら他のコースをそれぞれ終了させる必要があります。

修了証を取得

すべてのコースを終了し、実践型プロジェクトを完了すると、修了証を獲得します。この修了証は、今後採用企業やあなたの職業ネットワークと共有できます。

how it works

この専門講座には6コースあります。

コース1

Introduction to Systems Biology

4.3
290件の評価
53件のレビュー
This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses....
コース2

Experimental Methods in Systems Biology

4.6
163件の評価
25件のレビュー
Learn about the technologies underlying experimentation used in systems biology, with particular focus on RNA sequencing, mass spec-based proteomics, flow/mass cytometry and live-cell imaging. A key driver of the systems biology field is the technology allowing us to delve deeper and wider into how cells respond to experimental perturbations. This in turns allows us to build more detailed quantitative models of cellular function, which can give important insight into applications ranging from biotechnology to human disease. This course gives a broad overview of a variety of current experimental techniques used in modern systems biology, with focus on obtaining the quantitative data needed for computational modeling purposes in downstream analyses. We dive deeply into four technologies in particular, mRNA sequencing, mass spectrometry-based proteomics, flow/mass cytometry, and live-cell imaging. These techniques are often used in systems biology and range from genome-wide coverage to single molecule coverage, millions of cells to single cells, and single time points to frequently sampled time courses. We present not only the theoretical background upon which these technologies work, but also enter real wet lab environments to provide instruction on how these techniques are performed in practice, and how resultant data are analyzed for quality and content....
コース3

Network Analysis in Systems Biology

4.5
116件の評価
14件のレビュー
An introduction to data integration and statistical methods used in contemporary Systems Biology, Bioinformatics and Systems Pharmacology research. The course covers methods to process raw data from genome-wide mRNA expression studies (microarrays and RNA-seq) including data normalization, differential expression, clustering, enrichment analysis and network construction. The course contains practical tutorials for using tools and setting up pipelines, but it also covers the mathematics behind the methods applied within the tools. The course is mostly appropriate for beginning graduate students and advanced undergraduates majoring in fields such as biology, math, physics, chemistry, computer science, biomedical and electrical engineering. The course should be useful for researchers who encounter large datasets in their own research. The course presents software tools developed by the Ma’ayan Laboratory (http://labs.icahn.mssm.edu/maayanlab/) from the Icahn School of Medicine at Mount Sinai, but also other freely available data analysis and visualization tools. The ultimate aim of the course is to enable participants to utilize the methods presented in this course for analyzing their own data for their own projects. For those participants that do not work in the field, the course introduces the current research challenges faced in the field of computational systems biology....
コース4

Dynamical Modeling Methods for Systems Biology

4.7
129件の評価
25件のレビュー
An introduction to dynamical modeling techniques used in contemporary Systems Biology research. We take a case-based approach to teach contemporary mathematical modeling techniques. The course is appropriate for advanced undergraduates and beginning graduate students. Lectures provide biological background and describe the development of both classical mathematical models and more recent representations of biological processes. The course will be useful for students who plan to use experimental techniques as their approach in the laboratory and employ computational modeling as a tool to draw deeper understanding of experiments. The course should also be valuable as an introductory overview for students planning to conduct original research in modeling biological systems. This course focuses on dynamical modeling techniques used in Systems Biology research. These techniques are based on biological mechanisms, and simulations with these models generate predictions that can subsequently be tested experimentally. These testable predictions frequently provide novel insight into biological processes. The approaches taught here can be grouped into the following categories: 1) ordinary differential equation-based models, 2) partial differential equation-based models, and 3) stochastic models....

講師

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Eric Sobie, PhD

Associate Professor
Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY)
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Susana Neves, PhD

Assistant Professor
Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY)
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Ravi Iyengar, PhD

Dorothy H. and Lewis Rosenstiel Professor
Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY)
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Marc Birtwistle, PhD

Assistant Professor
Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY)
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Avi Ma’ayan, PhD

Director, Mount Sinai Center for Bioinformatics
Professor, Department of Pharmacological Sciences
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Iman Tavassoly, MD, PhD

Systems Biology Center New York (SBCNY)

マウントサイナイ医科大学(Icahn School of Medicine at Mount Sinai)について

The Icahn School of Medicine at Mount Sinai, in New York City is a leader in medical and scientific training and education, biomedical research and patient care....

よくある質問

  • はい。まず始めに興味のあるコースカードをクリックして登録します。コースに登録して修了することによって、共有できる修了証を取得するか、無料でコースを聴講してコースの教材を確認することができます。専門講座の一部であるコースにサブスクライブすると、専門講座全体に自動的にサブスクライブされます。進捗を追跡するには、受講生のダッシュボードにアクセスしてください。

  • このコースは完全にオンラインで提供されているため、実際に教室に出席する必要はありません。Webまたはモバイル機器からいつでもどこからでも講義、学習用教材、課題にアクセスできます。

  • この専門講座では大学の単位は付与されませんが、一部の大学では専門講座修了証を単位として承認する場合があります。詳細については、大学にお問い合わせください。

  • Time to completion can vary based on your schedule, but most learners are able to complete the Specialization in 12 months.

  • Some college-level cell and molecular biology, basic statistics and calculus.

  • The first (Introduction to Systems Biology) and last course (Integrated Analysis in Systems Biology) should be taken in sequence. There is flexibility in taking the middle three courses. These courses may be taken in any sequence, but are best taken in the order listed.

  • Coursera courses and certificates don't carry university credit, though some universities may choose to accept Specialization Certificates for credit. Check with your institution to learn more.

  • You will be able to design and implement systems biology methods to solve biomedical problems. The systems biology specialization covers all areas of systems biology in biomedical sciences.

  • You will have access to Matlab provided by MathWorks whenever it is needed. Other programs and softwares used in the courses are freely available.

さらに質問がある場合は、受講者向けヘルプセンターにアクセスしてください。