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初級レベル

約17時間で修了

英語

字幕:英語

100%オンライン

自分のスケジュールですぐに学習を始めてください。

柔軟性のある期限

スケジュールに従って期限をリセットします。

初級レベル

約17時間で修了

英語

字幕:英語

シラバス - 本コースの学習内容

1
3時間で修了

Week 1: Introduction to Evolutionary Tree Construction

<p>Welcome to our class!</p><p>In this class, we will consider the following two central biological&nbsp;questions (the computational approaches needed to solve them are shown in parentheses):</p><ol><li>Weeks 1-3: Which Animal Gave Us SARS? (<i>Evolutionary tree construction</i>)</li><li>Weeks 4-5: Was <em>T. rex</em> Just a Big Chicken?&nbsp;(<em>Combinatorial Algorithms</em>)</li></ol><p>In Week 6, you will complete a Bioinformatics Application Challenge to apply evolutionary tree construction algorithms in order to determine the origin of the recent ebola outbreak in Africa.</p><p>As in previous courses, each of these two chapters is accompanied by a Bioinformatics Cartoon created by talented artist Randall Christopher and serving as a chapter header in the Specialization's bestselling <a href="http://bioinformaticsalgorithms.com" target="_blank">print companion</a>. You can find the first chapter's cartoon at the bottom of this message. What do stick bugs and bats have to do with deadly viruses? And how can bioinformatics be used to stop these viruses in their tracks? Start learning today and find out!</p><p><img src="http://bioinformaticsalgorithms.com/images/cover/evolution_cropped.jpg" title="Image: http://bioinformaticsalgorithms.com/images/cover/evolution_cropped.jpg" width="528"></p>...
5件のビデオ (合計34分), 2 readings, 3 quizzes
5件のビデオ
The Fastest Outbreak 5 分
Transforming Distance Matrices into Evolutionary Trees 6 分
Toward an Algorithm for Distance-Based Phylogeny Construction 8 分
Additive Phylogeny 9 分
2件の学習用教材
Course Details10 分
Week 1 FAQs (Optional)
1の練習問題
Week 1 Quiz15 分
2
3時間で修了

Week 2: More Algorithms for Constructing Trees from Distance Matrices

<p>Welcome to Week 2 of class!</p> <p>Last week, we started to see how evolutionary trees can be constructed from distance matrices. &nbsp;This week, we will encounter additional algorithms for this purpose, including the neighbor-joining algorithm, which has become one of the top-ten most cited papers in all of science since its introduction three decades ago.</p>...
3件のビデオ (合計17分), 1 reading, 3 quizzes
3件のビデオ
Ultrametric Trees 6 分
The Neighbor-Joining Algorithm 7 分
1件の学習用教材
Week 2 FAQs (Optional)
1の練習問題
Week 2 Quiz15 分
3
4時間で修了

Week 3: Constructing Evolutionary Trees from Characters

<p>Welcome to week 3 of class!</p> <p>Over the last two weeks, we have seen several different algorithms for constructing evolutionary trees from distance matrices.</p> <p>This week, we will conclude the current chapter by considering what happens if we use properties called "characters" instead of distances. We will also see how to infer the ancestral states of organisms in an evolutionary tree, and consider whether it is possible to define an efficient algorithm for this task.</p>...
4件のビデオ (合計20分), 1 reading, 3 quizzes
4件のビデオ
The Small Parsimony Algorithm 8 分
The Large Parsimony Algorithm 3 分
Evolutionary Tree Reconstruction in the Modern Era 5 分
1件の学習用教材
Week 3 FAQs (Optional)
1の練習問題
Week 3 Quiz15 分
4
1時間で修了

Week 4

<p>Welcome to week 4 of the class!</p> <p>Did birds evolve from dinosaurs? Over the next two weeks, we will see how we could analyze molecular evidence in support of this theory. You can find this week's Bioinformatics Cartoon from Randall Christopher at the bottom of this E-mail. Why does the <em>T. rex&nbsp;</em>look so much like a chicken? And why is the monkey typing frantically? Keep learning to find out!</p> <p><img src="http://bioinformaticsalgorithms.com/images/cover/proteomics_cropped.jpg" title="Image: http://bioinformaticsalgorithms.com/images/cover/proteomics_cropped.jpg" width="528"></p>...
4件のビデオ (合計26分), 1 reading, 2 quizzes
4件のビデオ
Decoding an Ideal Spectrum 5 分
From Ideal to Real Spectra 5 分
Peptide Sequencing 7 分
1件の学習用教材
Note on This Week's Assignments10 分
1の練習問題
Week 4 Quiz15 分
5
1時間で修了

Week 5: Resolving the T. rex Peptides Mystery?

<p>Welcome to week 5 of class!</p> <p>Last week, we asked whether it is possible for dinosaur peptides to survive locked inside of a fossil for 65 million years. This week, we will see what this question has to do with statistics; in the process, we will see how a monkey typing out symbols on a typewriter can be used to address it.</p>...
5件のビデオ (合計44分), 1 reading, 2 quizzes
5件のビデオ
Spectral Dictionaries 6 分
The Ostrich Hemoglobin Riddle 15 分
Searching for Post-Translational Modifications 5 分
Spectral Alignment Algorithm 11 分
1件の学習用教材
Note on This Week's Content10 分
1の練習問題
Week 5 Quiz15 分
6
4時間で修了

Week 6: Bioinformatics Application Challenge

<p>Welcome to the sixth and final week of the course!</p> <p>In this week's Bioinformatics Application Challenge, we will use reconstruct an evolutionary tree of ebolaviruses and use it to determine the origin of the pathogen that caused the recent outbreak in Africa.</p>...
1 quiz
4.5
12件のレビューChevron Right

人気のレビュー

by RGJul 20th 2017

Covers the most important algorithms for phylogenetic trees. Fascinating exam

講師

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Pavel Pevzner

Professor
Department of Computer Science and Engineering
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Phillip Compeau

Visiting Researcher
Department of Computer Science & Engineering

カリフォルニア大学サンディエゴ校について

UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 10 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom—life is their laboratory....

バイオインフォマティクスの専門講座について

Join Us in a Top 50 MOOC of All Time! How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth? When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science. Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional! Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video. You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website. Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!...
バイオインフォマティクス

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